DEPARTMENT OF CHEMISTRY IN PHARMACY

History of the Department

From the establishment of the Faculty of Pharmacy in 1973/74 until 1992, classes for students in the field of natural sciences were delivered by teachers and associates from the Faculty of Science of the University of Sarajevo.

From 1993 to 2002, classes in courses in the field of natural sciences was delivered by teachers and teachinmg assistants permanently employed at the Faculty of Pharmacy. In this period, individual courses were designed as independent.

 The Department for science and mathematical courses in pharmacy of the Faculty of Pharmacy of the University of Sarajevo was formed in 2002, after the unification of courses from the area of science, which were studied at the Faculty of Pharmacy. In 2022, its name was changed to the Department of Chemistry in Pharmacy.

Teaching and professional staff currently involved in the teaching process: 

Šaćira Mandal Full Professor Google Scholar ORCID CV    |   CV-en	Aida Šapčanin Full Professor Google Scholar ORCID CV   |   CV-en	Hurija Džudžević-Čančar Full Professor Google Scholar ORCID CV   |   CV-en	Mirsada Salihović Full Professor Google Scholar ORCID CV   |   CV-en

Mirha Pazalja Associate Professor Google Scholar ORCID CV   |   CV-en	Alema Dedić Assistant Professor Google Scholar ORCID CV   |   CV-en	Emina Ramić Assistant Professor Google Scholar ORCID CV   |   CV-en	Amra Alispahić Assistant Professor Google Scholar ORCID CV   |   CV-en

Selma Korać Senior Assistant Google Scholar ORCID CV   |   CV-en	Mediha Čubro Senior Independent Laboratory Assistant	Mubera Pehlivanović Senior Laboratory Assistant	Melita Kurtović Laboratory Assistant

Teaching activities

The teachers and teaching assistants of the Department carry out theoretical and practical classes in the 1st, 2nd, 3rd and 5th years of the integrated study and the 3rd cycle of studies of the Faculty of Pharmacy from compulsory and elective courses, as follows: General Chemistry, Analytical Chemistry I, Analytical Chemistry II, Selected Chapters from Analytical Chemistry Chemistry – Bioanalytical Chemistry, Selected Chapters from Analytical Chemistry – Analysis of Trace Elements, Selected Chapters from Analytical Chemistry – Free Radicals and Antioxidants, Modern Approach to Research in Fatty Acid Analysis, Inorganic chemistry, Selected chapters from Inorganic chemistry – Chemistry of bioelements, Organic Chemistry I, Organic Chemistry II, Selected Chapters in Organic Chemistry – Mechanisms of the synthesis of biologically active compounds, Heterocycles in the structure of pharmaceutical active substances, Organic chemistry in drug synthesis, CSF biomarkers of Alzheimer's dementia, MAOS and extractions of of bioactive compounds, Microwave-assisted green synthesis of bioactive compounds, Chiral chromatography on natural materials, A modern approach to the extraction and analysis of volatiles from natural materials, Physical Chemistry I, Physical Chemistry II, Selected Chapters in Physical Chemistry – Colloidal Chemistry

Academic and professional activities

• Research in which members of the Department are involved is carried out within the framework of projects financed by the Ministry of Science, Higher Education and Youth of the Canton Sarajevo and the Federal Ministry of Education and Science of Bosnia and Herzegovina. The scientific interest of the Department's employees moves in several directions:improvement of analytical-chemical methods for measuring the antioxidant capacity of tissues and body fluids (ORAC and other spectrofluorimetric and photometric methods);
• free radicals and their role in neurodegeneration, especially in Parkinson's and Alzheimer's disease;
• natural antioxidants, polyphenols, flavonoids, anthocyanidins and anthocyanidin glycosides;
• the relationship between the structure and antioxidant activity of pure organic molecules and biomolecules;
• experimental models of Alzheimer's disease, diabetes mellitus and cerebral diseases, alloxan and streptozotocin model;
• analysis of inorganic and organic pollutants in soil and health risk assessments;
• analysis of free fatty acids – structure in health and disease and the development of specific and sensitive methods for the identification of fatty acids and their metabolic derivatives;
• research into the mechanism and signaling pathways of fatty acids involved in the regulation of the expression and activity of certain genes in type 2 diabetes mellitus and other diseases; future research is focused on fatty acids and free fatty acids in metabolomic and especially lipidomic research;
• synthesis and structural characterization of new acyclic nucleosides and their biological activity;
• electrochemical characterization of ruthenium complex compounds and development of new sensors for specific analytes using ruthenium complexes as mediators;
• analysis of inorganic pollutants in the air, biomonitoring of air quality, environmental chemistry, food chemistry and health risk assessments;
• electrocatalysis and material corrosion, synthesis of energy conversion and storage materials;
• determination of electrochemical parameters of polyelectrolytes and conducting polymers;
• detection and quantification of beta-amyloid and tau protein as the biomarkers of Alzheimer's disease in cerebrospinal fluid;
• acetylcholinesterase biosensor construction from conjugated polymers-nanoparticle composites for the detection of organophosphorus pesticides;
• microwave assisted organic synthesis of molecules with biological activity;
• microwave assisted extraction of natural products;
• application of green chemistry principles in the synthesis and extraction of bioactive compounds;
• preconcentration of heavy metals on Ce and Zr oxides modified with different reagents and their determination by AAS;
• determination of the mineral composition of natural products by the AAS method;
• protein phase stability analysis for application in the pharmaceutical and food industries;
• extraction of volatiles by headspace solid-phase microextraction on different adsorption fibers;
• chemical characterization of different plant extracts and essential oils by HPLC, GS-MS, Chiral chromatography, FTIR, and UV-vis spectrometry;
• in silico and in vitro determination of the antioxidative, antimicrobial, antifungal, and antiproliferative activity of natural products;
• in vitro determination of the cytotoxicity and genotoxicity of natural product samples against different human cancer cell lines;
• HPLC analysis of phytosterols;
• development and validation of a method for heavy metal detection in pharmaceutical products;
• development and validation of the method for phytosterol determination.